If you are getting and “Access Denied” denied error message when you are trying to use the MOSS 2007 Sharepoint Designer, you could try making yourself the site collection administrator.
From your Central Administration, go to “Application Management/Site collection administrators” and set yourself as the primary or secondary sit collection administrator.
I had some problems with the Logitech MX Master 3S Mouse with an M1 MacBook Pro, but I had better luck with a Logitech G502 X Mouse